Antiphospholipid syndrome presenting as cardiac failure

Antiphospholipid syndrome presenting as cardiac failure.

Sir, Antiphospholipid syndrome (APS) is a thrombo-philic disorder commonly associated with venous and arterial thrombosis, recurrent fetal loss and thrombocytopenia. Even though cardiac manifestations are well recognized, congestive cardiac failure (CCF) as an initial presenting feature is very uncommon. We present three cases presenting predominantly as cardiac failure where the diagnosis of A...

Antiphospholipid Syndrome Presenting with Superior Vena Cava Thrombosis

Primary antiphospholipid syndrome presenting as antiphospholipid syndrome nephropathy: a case report

INTRODUCTION Primary antiphospholipid syndrome can be a difficult diagnosis in the absence of typical clinical features. We describe an unusual presentation of primary antiphospholipid syndrome mimicking vasculitis for which the only diagnostic clue on initial presentation was antiphospholipid syndrome nephropathy. CASE PRESENTATION A 29-year-old Sri Lankan woman presented with features mimic...

Acute adrenal failure as the presenting feature of primary antiphospholipid syndrome in a child

INTRODUCTION Antiphospholipid syndrome (APS) is characterized by recurrent arterial and venous thrombosis and detection of antiphospholipid antibodies (aPLs). This syndrome may be associated with connective tissue disorders, or with malignancies, but it may also appear in isolated form (primary APS). We report on a pediatric patient presenting with acute adrenal failure as the first manifestati...

Acute adrenal failure (AAF) as the presenting symptom of primary antiphospholipid syndrome (APS)

Case report FV previously healthy 11-year-old boy, developed abdominal pain and fever. An abdominal computed tomography scan showed nodular lesions in the adrenal glands. He was referred to our Department, where the diagnosis of APS and adrenal failure were considered on the basis of the following laboratory findings: positive antiphospholipid antibodies (IgG 20,9 IgM 27,3 n.v. <10), high plasm...